Introducing small animal imaging devices:
Small animal PET:
An animal PET designed and constructed for PET imaging of small animals such as rats and mice.this system evaluates the metabolic and physiological functions of the animal body by estimating the distribution of radiopharmaceutical in the animal body .the system can be used to diagnose,evaluate ,estimates of progression of tumors,lesions and organs,function can be used.
Small animals SPECT:
The HiReSPECT is a small animal imaging system that provides researcher with high resolution 3D images of the physiological function of animal organs.the function of this device is that the radiopharmaceutical is injected into the rat vein, and then the device with its detector system provides a number of two dimensional images of different angles in the 360 degree range of rats.then a computer software,using the data obtained in a three_ dimensional image ,reconstructs the mode and extent of the radiopharmaceutical dispersion in the rat .using the obtained information ,one can comment on the effectiveness of the used radiopharmaciuticals and the target cells in the best way.
Sample picture of SPECT imaging:
click on the image to download the file for each image:
Heart image of the rat Lung image of the rat liver image of the rat
Thyroid image of the rat Kidney image of the rat
Molecular fluorescence device of small animal:
Molecular fluorescence tomography system with the aim of small animals imaging in the clinical and research fields can be used to identify metabolic pathways, issue structure and small animal studies.in this type of imaging,the study is at the molecular and even sub_molecular level in a non_invasive and non_invasive manner.the capabilities of this type of imaging can be used to diagnose and even treat some diseases ,such as cancer and cardiovascular disease.also , this technique can be used to improve the treatment and optimization of drugs in pre_clinical trials and then clinical users.
:Animal PET
| 120mm |
Bore opening |
| 50mm |
Axial field of view |
| 100mm |
Transaxial field of view |
| 10 |
Number of detector blocks |
| 1.8mm@center without resolution recovery |
Spatial resolution(mm) |
| 17% |
Energy resolution |
| LYSO |
Crystal material |
| 2x2x10mm |
Crystal dimension |
| 5760 |
Total number of detector elements |
| 24 |
Number of detector rings |
| SiPMT |
Light to signal converter |
| Ring |
Detector geometry |
| OSEM |
Reconstruction algorithm |
:Animal SPECT
| Comment |
Description |
Parameter |
| 4 Optional |
2 |
Number of Detector Heads |
| Pixelated |
CsI(Na) |
Crystal Material |
| Total Area |
100x50 mm2 |
Crystal Size |
| Separated by Epoxy |
1x1x5 mm3 |
Crystal Element Size |
| 0/2mm Inter Crystal Area |
1.2mm |
Crystal Element Pitch |
| Active Area |
96x45.6mm |
Active Area Per Detector Head |
| -- |
3040 |
Number of Crystal Elements Per Head |
| H8500(H9500optional) |
2 |
Number of PSPMTs Per Head |
| Hexagonal |
Parallel Hole |
Collimator Type |
| Hole x Septa x Hole xLenght |
1.2x0.2x34mm |
Collimator Specifications |
| -- |
0.1_+1.2 |
Intrinsic Spatial Resolution |
| At Minimum Distance |
0.2_+1.8 |
Spect System Resolution |
|
At Collimator Surface
|
0.1_+1.5 |
Planar Resolution |
: Animal Fluorescence
| 16MP CCD camera |
Camera and lens |
| 8x8 |
Detector Type |
| 8.4x9.8 |
Pixel size(w x h micro meter) |
| 1to18@13.5 MHz> |
Read noise(e-) |
| Max 12x12 |
FOV(cm) |
| f/1.1-f/16,30mm lens,xed |
Lens |
| 85%from500-650nm> ,>40%from650-850nm |
Quantum efficiency |
| 10oc ,air cooled- |
CCD operating temperature |
| 0.0003> |
Dark current (e/pixel/s) |
| 45 |
Minimum detectable radiance
(photons/sec/cm2/sr)
|
| 1x1, 2x2, 4x4, 8x8, 16x16 |
binning |
| 15fps at 1024 x 1024 pixels |
Frame rate |
| 10 |
Fluorescence emission filters |
| 80cm wide ,70cm deep, 90cm high |
Space requirements |
| Standard USB 2.0 high speed interface |
Interface connector |
| 0.5> |
(Resolution (mm |
| 6 |
Weight(Kg) |
